The Consortium for Top-Down Proteomics Launches a New Initiative to Develop the Human Proteoform Atlas

The Consortium for Top-Down Proteomics has launched a new Initiative to build the Human Proteoform Atlas, the definitive set of unique proteoforms capturing the diversity of proteins resulting from combinations of genetic polymorphisms, RNA splice variants, and post-translational modifications. This proteoform-specific information is critical to understanding the mechanisms of disease and to accelerate the development of more precise diagnostics and potential therapeutic agents.