What is the ProSight PC PScore?
In Data Analysis, asked by Montano Designs ears ago
Answers

The P Score is a statistical model of MS/MS matching based on the Poisson Distribution. If an event is expected to occur λ times, then the probability of it occurring k times is given by the Poisson distribution:
 If f is the total number of observed fragments, and n is the number of matching fragments, we may estimate the probability of a random protein match given f and n:
where x is the mean probability that a mass of an observed fragment ion will randomly match one from a generic protein. Given the probability of a random protein match with a particular n, f, and Ma, we can now estimate the probability of getting a match at least as good as we have by random chance:
where p is the pvalue assuming our Poisson model – what we call the P Score.
Please register/login to answer this question. Click here to login
Questions from category Data Analysis

0AnswersIn Data Analysis, asked by Alan Doucette 11 months ago

1AnswerIn Data Analysis, asked by Montano Designs ears ago
Are you sure you want to perform this operation?
