Publications

Mass spectrometry for the biophysical characterization of therapeutic monoclonal antibodies

Zhang H, Cui W, Gross ML "Mass spectrometry for the biophysical characterization of therapeutic monoclonal antibodies." FEBS Lett, 2014, 588(2) p. 308-17

PubMed: 24291257
PubMed Central: PMC3917544
DOI:10.1016/j.febslet.2013.11.027

Native Top-Down Electrospray Ionization-Mass Spectrometry of 158 kDa Protein Complex by High-Resolution Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Li H, Wolff JJ, Van Orden SL, Loo JA "Native top-down electrospray ionization-mass spectrometry of 158 kDa protein complex by high-resolution Fourier transform ion cyclotron resonance mass spectrometry." Anal Chem, 2014, 86(1) p. 317-20

PubMed: 24313806
PubMed Central: PMC3908771
DOI:10.1021/ac4033214

Identification of Ultramodified Proteins Using Top-Down Tandem Mass Spectra

Liu X, Hengel S, Wu S, Tolić N, Pasa-Tolić L, Pevzner PA "Identification of ultramodified proteins using top-down tandem mass spectra." J Proteome Res, 2013, 12(12) p. 5830-8

PubMed: 24188097
PubMed Central: PMC3905687
DOI:10.1021/pr400849y

Top-Down Mass Spectrometry on Tissue Extracts and Biofluids with Isoelectric Focusing and Superficially Porous Silica Liquid Chromatography

Zhang J, Roth MJ, Chang AN, Plymire DA, Corbett JR, Greenberg BM, Patrie SM "Top-down mass spectrometry on tissue extracts and biofluids with isoelectric focusing and superficially porous silica liquid chromatography." Anal Chem, 2013, 85(21) p. 10377-84

PubMed: 24074297
DOI:10.1021/ac402394w

Unequivocal Determination of Site-Specific Protein Disulfide Bond Reduction Potentials by Top-Down FTICR MS: Characterization of the N- and C-Terminal Redox-Active Sites in Human Thioredoxin 1

Scotcher J, Bythell BJ, Marshall AG "Unequivocal determination of site-specific protein disulfide bond reduction potentials by top-down FTICR MS: characterization of the N- and C-terminal redox-active sites in human thioredoxin 1." Anal Chem, 2013, 85(19) p. 9164-72

PubMed: 24040747
DOI:10.1021/ac401850p

Complete Protein Characterization Using Top-Down Mass Spectrometry and Ultraviolet Photodissociation

Shaw JB, Li W, Holden DD, Zhang Y, Griep-Raming J, Fellers RT, Early BP, Thomas PM, Kelleher NL, Brodbelt JS "Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation." J Am Chem Soc, 2013, 135(34) p. 12646-51

PubMed: 23697802
PubMed Central: PMC3757099
DOI:10.1021/ja4029654

Photodissociation and Dissociative Photoionization Mass Spectrometry of Proteins and Noncovalent Protein-Ligand Complexes

Canon F, Milosavljević AR, van der Rest G, Réfrégiers M, Nahon L, Sarni-Manchado P, Cheynier V, Giuliani A "Photodissociation and dissociative photoionization mass spectrometry of proteins and noncovalent protein-ligand complexes." Angew Chem Int Ed Engl, 2013, 52(32) p. 8377-81

PubMed: 23868751
DOI:10.1002/anie.201304046

Automated Analysis of Hemoglobin Variants Using NanoLC-MS and Customized Databases

Das R, Mitra G, Mathew B, Ross C, Bhat V, Mandal AK "Automated analysis of hemoglobin variants using nanoLC-MS and customized databases." J Proteome Res, 2013, 12(7) p. 3215-22

PubMed: 23692286
DOI:10.1021/pr4000625

Significant Modifications of the Salivary Proteome Potentially Associated with Complications of Down Syndrome Revealed by Top-down Proteomics

Cabras T, Pisano E, Montaldo C, Giuca MR, Iavarone F, Zampino G, Castagnola M, Messana I "Significant modifications of the salivary proteome potentially associated with complications of Down syndrome revealed by top-down proteomics." Mol Cell Proteomics, 2013, 12(7) p. 1844-52

PubMed: 23533003
PubMed Central: PMC3708170
DOI:10.1074/mcp.M112.026708

Top-down proteomics reveals a unique protein S-thiolation switch in Salmonella Typhimurium in response to infection-like conditions

Ansong C, Wu S, Meng D, Liu X, Brewer HM, Deatherage Kaiser BL, Nakayasu ES, Cort JR, Pevzner P, Smith RD, Heffron F, Adkins JN, Pasa-Tolic L "Top-down proteomics reveals a unique protein S-thiolation switch in Salmonella Typhimurium in response to infection-like conditions." Proc Natl Acad Sci U S A, 2013, 110(25) p. 10153-8

PubMed: 23720318
PubMed Central: PMC3690903
DOI:10.1073/pnas.1221210110

Multipurpose Dissociation Cell for Enhanced ETD of Intact Protein Species

Rose CM, Russell JD, Ledvina AR, McAlister GC, Westphall MS, Griep-Raming J, Schwartz JC, Coon JJ, Syka JE "Multipurpose dissociation cell for enhanced ETD of intact protein species." J Am Soc Mass Spectrom, 2013, 24(6) p. 816-27

PubMed: 23609185
PubMed Central: PMC3667591
DOI:10.1007/s13361-013-0622-0

Top-Down Structural Analysis of an Intact Monoclonal Antibody by Electron Capture Dissociation-Fourier Transform Ion Cyclotron Resonance-Mass Spectrometry

Mao Y, Valeja SG, Rouse JC, Hendrickson CL, Marshall AG "Top-down structural analysis of an intact monoclonal antibody by electron capture dissociation-Fourier transform ion cyclotron resonance-mass spectrometry." Anal Chem, 2013, 85(9) p. 4239-46

PubMed: 23551206
DOI:10.1021/ac303525n

Identification of New Apolipoprotein-CIII Glycoforms with Ultrahigh Resolution MALDI-FTICR Mass Spectrometry of Human Sera

Nicolardi S, van der Burgt YE, Dragan I, Hensbergen PJ, Deelder AM "Identification of new apolipoprotein-CIII glycoforms with ultrahigh resolution MALDI-FTICR mass spectrometry of human sera." J Proteome Res, 2013, 12(5) p. 2260-8

PubMed: 23527852
DOI:10.1021/pr400136p

Characterization and Quantification of Intact 26S Proteasome Proteins by Real-Time Measurement of Intrinsic Fluorescence Prior to Top-down Mass Spectrometry

Russell JD, Scalf M, Book AJ, Ladror DT, Vierstra RD, Smith LM, Coon JJ "Characterization and quantification of intact 26S proteasome proteins by real-time measurement of intrinsic fluorescence prior to top-down mass spectrometry." PLoS One, 2013, 8(3) p. e58157

PubMed: 23536786
PubMed Central: PMC3594244
DOI:10.1371/journal.pone.0058157

Top-down Targeted Proteomics for Deep Sequencing of Tropomyosin Isoforms

Peng Y, Chen X, Zhang H, Xu Q, Hacker TA, Ge Y "Top-down targeted proteomics for deep sequencing of tropomyosin isoforms." J Proteome Res, 2013, 12(1) p. 187-98

PubMed: 23256820
PubMed Central: PMC3596867
DOI:10.1021/pr301054n