Publications

A whole-molecule immunocapture LC-MS approach for the in vivo quantitation of biotherapeutics

Kellie JF, Kehler JR, Mencken TJ, Snell RJ, Hottenstein CS "A whole-molecule immunocapture LC-MS approach for the in vivo quantitation of biotherapeutics." Bioanalysis, 2016, 8(20) p. 2103-14

PubMed: 27611496
DOI:10.4155/bio-2016-0180

Top-down analysis of protein samples by de novo sequencing techniques

Vyatkina K, Wu S, Dekker LJ, VanDuijn MM, Liu X, Tolić N, Luider TM, Paša-Tolić L, Pevzner PA "Top-down analysis of protein samples by de novo sequencing techniques." Bioinformatics, 2016, 32(18) p. 2753-9

PubMed: 27187201
DOI:10.1093/bioinformatics/btw307

MALDI Imaging of Liquid Extraction Surface Analysis Sampled Tissue

Randall EC, Race AM, Cooper HJ, Bunch J "MALDI Imaging of Liquid Extraction Surface Analysis Sampled Tissue." Anal Chem, 2016, 88(17) p. 8433-40

PubMed: 27447021
DOI:10.1021/acs.analchem.5b04281

Proteomic characterization of the acid-insoluble fraction of whole saliva from preterm human newborns

Arba M, Iavarone F, Vincenzoni F, Manconi B, Vento G, Tirone C, Cabras T, Castagnola M, Messana I, Sanna MT "Proteomic characterization of the acid-insoluble fraction of whole saliva from preterm human newborns." J Proteomics, 2016, 146() p. 48-57

PubMed: 27321913
DOI:10.1016/j.jprot.2016.06.021

Top-down venomics of the East African green mamba, Dendroaspis angusticeps, and the black mamba, Dendroaspis polylepis, highlight the complexity of their toxin arsenals

Petras D, Heiss P, Harrison RA, Süssmuth RD, Calvete JJ "Top-down venomics of the East African green mamba, Dendroaspis angusticeps, and the black mamba, Dendroaspis polylepis, highlight the complexity of their toxin arsenals." J Proteomics, 2016, 146() p. 148-64

PubMed: 27318176
DOI:10.1016/j.jprot.2016.06.018

Rapid phenotype hemoglobin screening by high-resolution mass spectrometry on intact proteins

Helmich F, van Dongen JL, Kuijper PH, Scharnhorst V, Brunsveld L, Broeren MA "Rapid phenotype hemoglobin screening by high-resolution mass spectrometry on intact proteins." Clin Chim Acta, 2016, 460() p. 220-6

PubMed: 27417394
DOI:10.1016/j.cca.2016.07.006

Label-Free Relative Quantitation of Isobaric and Isomeric Human Histone H2A and H2B Variants by Fourier Transform Ion Cyclotron Resonance Top-Down MS/MS

Dang X, Singh A, Spetman BD, Nolan KD, Isaacs JS, Dennis JH, Dalton S, Marshall AG, Young NL "Label-Free Relative Quantitation of Isobaric and Isomeric Human Histone H2A and H2B Variants by Fourier Transform Ion Cyclotron Resonance Top-Down MS/MS." J Proteome Res, 2016, 15(9) p. 3196-203

PubMed: 27431976
DOI:10.1021/acs.jproteome.6b00414

Combined Infrared Multiphoton Dissociation with Ultraviolet Photodissociation for Ubiquitin Characterization.

Halim MA, Girod M, MacAleese L, Lemoine J, Antoine R, Dugourd P "Combined Infrared Multiphoton Dissociation with Ultraviolet Photodissociation for Ubiquitin Characterization." J Am Soc Mass Spectrom, 2016, 27(9) p. 1435-42

PubMed: 27287047
PubMed Central: PMC5031736
DOI:10.1007/s13361-016-1419-8

2D FT-ICR MS of Calmodulin: A Top-Down and Bottom-Up Approach

Floris F, van Agthoven M, Chiron L, Soulby AJ, Wootton CA, Lam YP, Barrow MP, Delsuc MA, O'Connor PB "2D FT-ICR MS of Calmodulin: A Top-Down and Bottom-Up Approach." J Am Soc Mass Spectrom, 2016, 27(9) p. 1531-8

PubMed: 27431513
DOI:10.1007/s13361-016-1431-z

Characterization of the Protein Components of Matrix Stones Sheds Light on S100-A8 and S100-A9 Relevance in the Inflammatory Pathogenesis of These Rare Renal Calculi

Martelli C, Marzano V, Iavarone F, Huang L, Vincenzoni F, Desiderio C, Messana I, Beltrami P, Zattoni F, Ferraro PM, Buchholz N, Locci G, Faa G, Castagnola M, Gambaro G "Characterization of the Protein Components of Matrix Stones Sheds Light on S100-A8 and S100-A9 Relevance in the Inflammatory Pathogenesis of These Rare Renal Calculi." J Urol, 2016, 196(3) p. 911-8

PubMed: 27113968
DOI:10.1016/j.juro.2016.04.064

193 nm Ultraviolet Photodissociation Mass Spectrometry of Tetrameric Protein Complexes Provides Insight into Quaternary and Secondary Protein Topology

Morrison LJ, Brodbelt JS "193 nm Ultraviolet Photodissociation Mass Spectrometry of Tetrameric Protein Complexes Provides Insight into Quaternary and Secondary Protein Topology." J Am Chem Soc, 2016, 138(34) p. 10849-59

PubMed: 27480400
DOI:10.1021/jacs.6b03905

Symmetry of Charge Partitioning in Collisional and UV Photon Induced Dissociation of Protein Assemblies

Tamara S, Dyachenko A, Fort KL, Makarov AA, Scheltema RA, Heck AJ "Symmetry of Charge Partitioning in Collisional and UV Photon-Induced Dissociation of Protein Assemblies." J Am Chem Soc, 2016, 138(34) p. 10860-8

PubMed: 27480281
DOI:10.1021/jacs.6b05147

Complete De Novo Assembly of Monoclonal Antibody Sequences

Tran NH, Rahman MZ, He L, Xin L, Shan B, Li M "Complete De Novo Assembly of Monoclonal Antibody Sequences." Sci Rep, 2016, 6() p. 31730

PubMed: 27562653
PubMed Central: PMC4999880
DOI:10.1038/srep31730

Epiproteomics: quantitative analysis of histone marks and codes by mass spectrometry

Zheng Y, Huang X, Kelleher NL "Epiproteomics: quantitative analysis of histone marks and codes by mass spectrometry." Curr Opin Chem Biol, 2016, 33() p. 142-50

PubMed: 27371874
PubMed Central: PMC5129744
DOI:10.1016/j.cbpa.2016.06.007

A workflow for absolute quantitation of large therapeutic proteins in biological samples at intact level using LC-HRMS

Jian W, Kang L, Burton L, Weng N "A workflow for absolute quantitation of large therapeutic proteins in biological samples at intact level using LC-HRMS." Bioanalysis, 2016, 8(16) p. 1679-91

PubMed: 27487386
DOI:10.4155/bio-2016-0096

Top-down Proteomics: Technology Advancements and Applications to Heart Diseases

Cai W, Tucholski TM, Gregorich ZR, Ge Y "Top-down Proteomics: Technology Advancements and Applications to Heart Diseases." Expert Rev Proteomics, 2016, 13(8) p. 717-30

PubMed: 27448560
PubMed Central: PMC5026638
DOI:10.1080/14789450.2016.1209414

Native Mass Spectrometry in Fragment-Based Drug Discovery

Pedro L, Quinn RJ "Native Mass Spectrometry in Fragment-Based Drug Discovery." Molecules, 2016, 21(8) p.

PubMed: 27483215
DOI:10.3390/molecules21080984

Characterization of Proteoforms with Unknown Post-translational Modifications Using the MIScore

Kou Q, Zhu B, Wu S, Ansong C, Tolić N, Paša-Tolić L, Liu X "Characterization of Proteoforms with Unknown Post-translational Modifications Using the MIScore." J Proteome Res, 2016, 15(8) p. 2422-32

PubMed: 27291504
DOI:10.1021/acs.jproteome.5b01098

Automated SDS Depletion for Mass Spectrometry of Intact Membrane Proteins though Transmembrane Electrophoresis

Kachuk C, Faulkner M, Liu F, Doucette AA "Automated SDS Depletion for Mass Spectrometry of Intact Membrane Proteins though Transmembrane Electrophoresis." J Proteome Res, 2016, 15(8) p. 2634-42

PubMed: 27376408
DOI:10.1021/acs.jproteome.6b00199

Top-Down Targeted Proteomics Reveals Decrease in Myosin Regulatory Light-Chain Phosphorylation That Contributes to Sarcopenic Muscle Dysfunction

Gregorich ZR, Peng Y, Cai W, Jin Y, Wei L, Chen AJ, McKiernan SH, Aiken JM, Moss RL, Diffee GM, Ge Y "Top-Down Targeted Proteomics Reveals Decrease in Myosin Regulatory Light-Chain Phosphorylation That Contributes to Sarcopenic Muscle Dysfunction." J Proteome Res, 2016, 15(8) p. 2706-16

PubMed: 27362462
PubMed Central: PMC4975644
DOI:10.1021/acs.jproteome.6b00244

Infrared Laser Activation of Soluble and Membrane Protein Assemblies in the Gas Phase

Mikhailov VA, Liko I, Mize TH, Bush MF, Benesch JL, Robinson CV "Infrared Laser Activation of Soluble and Membrane Protein Assemblies in the Gas Phase." Anal Chem, 2016, 88(14) p. 7060-7

PubMed: 27328020
DOI:10.1021/acs.analchem.6b00645

Intact Protein Quantitation Using Pseudoisobaric Dimethyl Labeling

Fang H, Xiao K, Li Y, Yu F, Liu Y, Xue B, Tian Z "Intact Protein Quantitation Using Pseudoisobaric Dimethyl Labeling." Anal Chem, 2016, 88(14) p. 7198-205

PubMed: 27359340
DOI:10.1021/acs.analchem.6b01388

Combining high-throughput MALDI-TOF mass spectrometry and isoelectric focusing gel electrophoresis for virtual 2D gel-based proteomics

Lohnes K, Quebbemann NR, Liu K, Kobzeff F, Loo JA, Ogorzalek Loo RR "Combining high-throughput MALDI-TOF mass spectrometry and isoelectric focusing gel electrophoresis for virtual 2D gel-based proteomics." Methods, 2016, 104() p. 163-9

PubMed: 26826592
PubMed Central: PMC4930893
DOI:10.1016/j.ymeth.2016.01.013

LESA FAIMS Mass Spectrometry for the Spatial Profiling of Proteins from Tissue

Griffiths RL, Creese AJ, Race AM, Bunch J, Cooper HJ "LESA FAIMS Mass Spectrometry for the Spatial Profiling of Proteins from Tissue." Anal Chem, 2016, 88(13) p. 6758-66

PubMed: 27228471
DOI:10.1021/acs.analchem.6b01060

Mass spectrometry locates local and allosteric conformational changes that occur on cofactor binding

Beveridge R, Migas LG, Payne KA, Scrutton NS, Leys D, Barran PE "Mass spectrometry locates local and allosteric conformational changes that occur on cofactor binding." Nat Commun, 2016, 7() p. 12163

PubMed: 27418477
PubMed Central: PMC4947166
DOI:10.1038/ncomms12163