Proteomic developments in the analysis of formalin-fixed tissue.

Proteomic developments in the analysis of formalin-fixed tissue.

Proteomic developments in the analysis of formalin-fixed tissue.

Biochim Biophys Acta. 2014 Oct 11;

Authors: Gustafsson OJ, Arentz G, Hoffmann P

Abstract
Retrospective proteomic studies, including those which aim to elucidate the molecular mechanisms driving cancer, require the assembly and characterization of substantial patient tissue cohorts. The difficulty of

...

Fragmentation Follows Structure: Top-Down Mass Spectrometry Elucidates the Topology of Engineered Cystine-Knot Miniproteins.

Related Articles

Fragmentation Follows Structure: Top-Down Mass Spectrometry Elucidates the Topology of Engineered Cystine-Knot Miniproteins.

PLoS One. 2014;9(10):e108626

Authors: Reinwarth M, Avrutina O, Fabritz S, Kolmar H

Abstract
Over the last decades the field of pharmaceutically relevant peptides has enormously expanded. Among them, several peptide families exist that contain

...

[Proteomic methods of protein separation and analysis].

Related Articles

[Proteomic methods of protein separation and analysis].

Zh Mikrobiol Epidemiol Immunobiol. 2014 May-Jun;(3):107-14

Authors:

Abstract
The review briefly presents principles and stages of execution of such highly effective methods of protein separation as capillary, 2D gel-electrophoresis, liquid chromatography, the possibility of their successful combination with tandem mass-spectrometry and

...

Simultaneous characterization of sequence polymorphisms, glycosylation and phosphorylation of fibrinogen in a direct analysis by LC-MS.

Simultaneous characterization of sequence polymorphisms, glycosylation and phosphorylation of fibrinogen in a direct analysis by LC-MS. Related Articles

Simultaneous characterization of sequence polymorphisms, glycosylation and phosphorylation of fibrinogen in a direct analysis by LC-MS.

Biochim Biophys Acta. 2014 Sep 30;

Authors: Nagel T, Meyer B

Abstract
Fibrinogen is an abundant plasma glycoprotein involved in pathologically important processes like blood clotting, hemostasis and angiogenesis. Sequence polymorphisms

...

Domain

This subsection of the ‘Family and Domains’ section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.

Protein domains often correspond to structural domains which are self-stabilizing and fold independently of the rest

...