Site-Specific Characterization and Absolute Quantification of Pegfilgrastim Oxidation by Top-Down High-Performance Liquid Chromatography-Mass Spectrometry.
Anal Chem. 2015 Aug 26;
Authors: Forstenlehner IC, Holzmann J, Toll H, Huber CG
The characterization and absolute quantification of protein biopharmaceuticals and their product-related impurities, e.g. oxidation variants, is essential due
Integration of electrochemistry with ultra-performance liquid chromatography/mass spectrometry.
Eur J Mass Spectrom (Chichester, Eng). 2015;21(3):341-51
Authors: Cai Y, Zheng Q, Liu Y, Helmy R, Loo JA, Chen H
This study presents the development of ultra-performance liquid chromatography (UPLC) mass spectrometry (MS) combined with electrochemistry (EC) for
Native top-down mass spectrometry for the structural characterization of human hemoglobin.
Eur J Mass Spectrom (Chichester, Eng). 2015;21(3):221-31
Authors: Zhang J, Reza Malmirchegini G, Clubb RT, Loo JA
Native mass spectrometry (MS) has become an invaluable tool for the characterization of proteins and noncovalent protein complexes
Top-down proteomic identification of Shiga toxin 2 subtypes from Shiga toxin-producing Escherichia coli by matrix-assisted laser desorption ionization-tandem time of flight mass spectrometry.
Appl Environ Microbiol. 2014 May;80(9):2928-40
Authors: Fagerquist CK, Zaragoza WJ, Sultan O, Woo N, Quiñones B, Cooley MB, Mandrell RE
We have analyzed
- Genalyte to Use $44M Funding Round to Pursue FDA Clearance for Multiplexed Immunoassay Device
- Approach to characterization of the higher order structure of disulfide-containing proteins using hydrogen/deuterium exchange and top-down mass spectrometry.
- Regional Isolation Drives Diversification of Bacteria in Cystic Fibrosis Lungs