Benchmarking multiple fragmentation methods on an Orbitrap Fusion for top-down phospho-proteoform characterization.
Anal Chem. 2015 Mar 24;
Authors: Brunner AM, Lossl P, Liu F, Huguet R, Mullen C, Yamashita M, Zabrouskov V, Makarov A, Altelaar AF, Heck AJ
Top-down analysis of intact proteins by mass spectrometry provides an
Cutting-edge mass spectrometry characterization of originator, biosimilar and biobetter antibodies.
J Mass Spectrom. 2015 Feb;50(2):285-97
Authors: Beck A, Debaene F, Diemer H, Wagner-Rousset E, Colas O, Dorsselaer AV, Cianférani S
The approval process for antibody biosimilars relies primarily on comprehensive analytical data to establish comparability and high similarity
Bottom-up and top-down solid-state NMR approaches for bacterial biofilm matrix composition.
J Magn Reson. 2015 Apr;253:91-7
Authors: Cegelski L
The genomics and proteomics revolutions have been enormously successful in providing crucial "parts lists" for biological systems. Yet, formidable challenges exist in generating complete descriptions of how the parts