The program begins on Sunday, June 9 with tutorial lectures at 5:00 pm and the opening session and plenary lecture at 6:45 pm. A Welcome Reception in the poster/exhibit hall will follow. Monday through Thursday will be full program days of concurrent oral sessions, poster sessions, and workshops. Poster sessions are scheduled 10:30 am to 2:30 pm to allow four hours of viewing. The program will conclude on Thursday, June 13 with a plenary lecture followed by a Closing Gala at the Convention Center (ticket required).

Co-Organizers: Neil L Kelleher, Northwestern University and Ljiljana Paša-Tolić, PNNL Top Down mass spectrometry is a classical approach to molecular analysis, but is reborn in the contemporary context of protein analysis. Top Down now stands at a turning point – somewhat beyond an emerging technology, but yet difficult to implement vs. more widely used Bottom Up approaches to protein and proteome interrogation. For proteomics, Top Down strives to preserve the forms of proteins present in vivo by measuring them intact, rather than measuring peptides produced from them by proteolysis, with the largest impact thus far felt in chromatin biology via Top Down and Middle Down analysis of histones. For single biopharmaceutical targets that are highly modified, Top Down continues its acceleration toward an accepted, even wide-spread practice. This meeting will bring together novice and seasoned practitioners in the field of Top Down mass spectrometry with the goal to outline recent approaches and applications and provide an outlook for its future.

The Local Organizing Committee and the Mass Spectrometry Society of Japan (MSSJ) welcome you all to attend the 19th IMSC. It is a particular honor that this landmark event - the first IMSC to be held outside Europe - will be staged in Asia. Indeed, the conference city, Kyoto, is one of the leading Asian cities. It is not only renowned as former capital and culture heart of Japan, but also for its place at the cutting edge of mass spectrometry research. The long history can be seen today in 17 UNESCO World Cultural Heritage Sites, fascinating traditions, cozy workshops, and sumptuous dining; the bright future in state of the art research institutions. The 19th IMSC will demonstrate the mass spectrometry community to be a global body.

Hynes Convention Center, Boston, Massachusetts We look forward to welcoming you to the beautiful and historic city of Boston. The Hynes Convention Center and Sheraton Boston hotel are located in the heart of Boston's Back Bay. A district known for its restaurants, nightlife and cultural attractions. It's about the SCIENCE! Featured speakers from across the globe will deliver talks on their recent and emerging research. The program includes slots for over 100 talks to be selected from contributed abstracts.